Anaphase II: After the two chromosomes in each daughter cell line up on the metaphase plate in Metaphase II, the final segregation of sister chromatids occurs. Note that the mother cell prior to meioisis was heterozygous (genotype: A/a;B/b).

The two copies of the metacentric chromosome where gene A is located are not identical, because a crossing over event occurred during Prophase I. The segregated sister chromatids from this chromosome are shown in the cell drawn on the left. The segregated sister chromatids of the acrocentric chromosome where gene B is located are also shown in the cell drawn on the right. From the four choices shown at the left, choose the other chromosomes that you expect to be found in the cell drawn on the right. Drag the appropriate chromatid first to P1. If you choose correctly (there may be more than one correct choice), a congratulatory message will appear, and the yellow box will become green. If you choose incorrectly, you will be asked to try to make another choice. Next, choose the chromosomes that you expect to be found in positions P2, P3 and P4 (again there may be more than one correct choice).

Please try to explain why only some arrangements of chromosomes are possible due to the processes of crossing over and independent assortment that happen during meiosis.

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